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KMID : 0363620220430040008
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Journal of Korean Oriental Medicine
2022 Volume.43 No. 4 p.8 ~ p.19
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A traditional East Asian herbal complex, Majainhwan for constipation in Parkinson’s disease: A retrospective study
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Cho Jun-Ho
Jin Chul
Kwon Seung-Won
Cho Seung-Yeon
Park Seong-Uk
Jung Woo-Sang
Mun Sang-Kwan
Park Jung-Mi
Ko Chang-Nam
Cho Ki-Ho
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Abstract
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Objectives:Parkinson’s disease (PD) patients experience various non-motor symptoms, among which constipation is the second most common after anosmia. However, there are no clear guidelines or effective treatment for constipation in PD.
Methods:To investigate the efficacy of Majainhwan (MH) on constipation in patients with PD, we conducted a retrospective chart review study of PD or Parkinsonism patients with constipation who received outpatient or inpatient treatment and whose previous laxatives were replaced by MH from August 2016 to July 2019.
Results:In this study, a total of 68 patients’ medical records were reviewed. Among the 44 outpatients with MH treatment, “effective” results were observed in 86.4% patients. Similarly, among the 24 inpatients, “effective” results were noted in 95.8% patients. The adverse effect was “diarrhea” reported in five cases.
Conclusion:Based on these findings, we could suggest that MH is relatively safe and may be effective in the treatment of constipation in patients with PD.
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KEYWORD
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Majainhwan, Mashiningan, Mazirenwan, Constipation, Parkinson’s disease
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